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The immunotherapy agent axalimogene filolisbac (AXAL) was created by attenuating a strain of Listeria monocytogenes to specifically target neoplastic cells infected with HPV

New England Journal of Medicine (2023) 2

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Applications Gut healing BPC-157 was originally characterized for gastric protection

No obvious toxicity has been reported in rodent studies at effective doses

Since NAD + is present in only catalytic amounts in the cell and is an essential cofactor for glycolysis (and other reactions), there must be a mechanism for regeneration of NAD + if glycolysis is to continue